LIPID
IN LIFE
Lipid is one of a group of organic compounds found in plants, animals, or
humans and are very useful for human life. Lipid compounds do not have a
formula similar structure or similar. Kimi properties and biological functions
also vary. Subcutaneous tissue around the abdomen, the fat tissue around the
kidneys contain a lot of lipids, especially fatty approximately 90%, in brain
tissue lipid atal the eggs are about the size of 7.5 to 30%. Therefore, this
paper compiled under the title "LIPID" to know more about lipid.
Lipid functions are: • As a constituent structure of cell membranes • In this
lipid acts as a barrier to cells and regulate the flow of materials • As •
Lipid energy reserves stored as adipose tissue • As hormaon and vitamins •
Hormone regulate communication between cells, while vitamin help the regulation
of biological processes.
Fat storage and use re-fatty acids will be stored
when not needed to meet energy needs. The main storage is adipose tissue fatty
acids. As for the storage stages are: - Fatty acids are transported from the
liver as VLDL complex. - Fatty acids are then converted into triglycerides in
adipose cells for storage. - Glycerol 3-phosphate needed to make triglycerides.
It should be available from glucose. - As a result, we can not store excess fat
if there is no glucose in the body. Lipid dynamics in adipose cells. Consider
the stages of the synthesis and degradation of triglyceride If energy demand
can not be fulfilled by carbohydrates, the deposit of triglycerides can be used
again. Triglycerides are broken down into glycerol and fatty acids. Glycerol
can be a source of energy (see metabolism of glycerol). While fatty acids would
be oxidized to meet the energy needs as well (see the beta oxidation).
Disease of lipid
a. Disease Niemann-Pick is a hereditary disease in
which there is a deficiency of a particular enzyme resulting in accumulation of
sphingomyelin (fat metabolism) or there is an abnormal accumulation of
cholesterol
b. Gaucher disease, glucocerebroside, which results in
fat metabolism, accumulate in the tissues. Gaucher disease is the most common
lipidosis. The disease is most common in people of Ashkenazi Jewish (Eastern
European). Gaucher disease causes enlargement of the liver and spleen and brown
coloration of the skin. Stacking glucocerebroside in the eye causes yellow
spots called pingueculae be seen. Stacking the cartilage can cause pain and
destroy the bone.
Gaucher disease occurs because of irregularities lysosomal enzymes, can be treated with injections of the enzyme for 2 weeks but this is not very effective. Is the treatment of this disease can be done permanently?
BalasHapusthe disease can be carried out removal of the spleen, but only to treat anemia, white blood cell count is low, low platelet and discomfort associated with an enlarged spleen. but for actions that occur in less know my heart.
BalasHapusfor permanently medician we can shared the back bond. but with high technology. we have to make syntetic back bond that have much glucocerebrosidase enzim. so we dont need to wait back bond shared from our family.
BalasHapus
BalasHapusGaucher disease is a genetic disease in which lipids accumulate in specific cells or organs. The disease is caused by deficiency of the enzyme that functions to solve glukoserebrosida glukoserebrosidase. So I think this disease can be cured by increasing the intake of enzymes glukoserebrosidase or we can use a protein that breaks glukosererosida.
by bone marrow taransplantasi.
BalasHapusBone marrow transplantation can also be performed. Blood-forming cells destroyed by Gaucher disease is removed and replaced. It can reverse many of the signs and symptoms that affected individuals suffer.